Steroides gonadiques

SUMMARY Basal concentrations of FSH, LH, testosterone, Δ4 androstenedione and dihydrotestosterone, together with FSH and LH responses to single injections of LHRH were determined in eighty‐four patients with oligospermia and in twenty‐seven normal men. LHRH responses were heterogeneous and indicate that various disorders might cause this syndrome. In six cases there appeared to be an isolated deficiency in spermatogenesis, as indicated by an increased FSH response, whilst the LH response was normal as were the concentrations of the testicular hormones. In twenty cases a concomitant disorder of Leydig cell function and spermatogenesis is suggested as indicated by increased FSH and LH responses and decreased concentrations of testosterone and Δ4 androstenedione (six) or concentrations at the lower limit of normal (fourteen). Furthermore, in five cases a hypothalamic and/or pituitary disturbance may be accepted on the basis of normal or decreased basal concentrations decreased and responses to LHRH with decreased concentrations of testosterone and Δ4 androstenedione. Finally, in thirty‐seven cases, oligospermia was not associated with any modification basal gonadotrophin concentrations or response to LHRH when compared with normal subjects.

La réaction inflammatoire cutanée reste localisée aux points d'administration des deux formulations vaccinales et se traduit sous la forme de papules bien circonscrites à l'examen externe. Son développement interne reste limité au derme superficiel. Elle disparaît sans laisser de granulome apparent au moment de l'abattage des animaux. La réaction inflammatoire, limitée dans le temps et aux points d'administration, traduit la tolérance aux deux formulations vaccinales et est obtenue par l'administration transcutanée de celles-ci, effectuée à l'aide d'un injecteur sans aiguille.


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Steroides gonadiques

steroides gonadiques


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