The majority of side effects from topical steroids occur within the nose at the site of local application. These side effects commonly include nasal irritation and nose bleeds . Should these symptoms occur, a person should stop using the nasal steroid for a few days, and then re-start the medication using the appropriate technique . If bleeding and irritation continue to occur, the nasal steroid should not be used any longer. A person who continues to use a nasal steroid despite these local side effects is at risk for septal perforation .
There were 12,679 eligible patients (651 MM; 2285 MAT; 9743 AM). Compared with the reference cohort AM, during the 3- to 30-day postindex period, lower adjusted odds (p < ) of having one or more rhinosinusitis-related medical encounters was observed for MM (odds ratio [OR] = ; 95% CI, -) and MAT (OR = ; 95% CI, -); having one or more rhinosinusitis-related prescriptions for MM (OR = ; 95% CI, -) and MAT (OR = ; 95% CI, -); having one or more antibiotic, nasal steroid, or oral steroid prescriptions for MM (OR = ; 95% CI, -) and MAT (OR = ; 95% CI, -); and having one or more antibiotic prescriptions for MM (OR = ; 95% CI, -) and MAT (OR = ; 95% CI, (-).