Of 79,985 patients, 73,765 (92%) were initially treated with intravenous steroids, whereas 6220 (8%) received oral treatment. We found that % (95% confidence interval [CI], %-%) of the intravenously and % (95% CI, %-%) of the orally treated patients died during hospitalization, whereas % (95% CI, %-%) of the intravenously and % (95% CI, %-%) of the orally treated patients experienced the composite outcome. After multivariable adjustment, including the propensity for oral treatment, the risk of treatment failure among patients treated orally was not worse than for those treated intravenously (odds ratio [OR], ; 95% CI, -). In a propensity-matched analysis, the risk of treatment failure was significantly lower among orally treated patients (OR, ; 95% CI, -), as was length of stay and cost. Using an adaptation of the instrumental variable approach, increased rate of treatment with oral steroids was not associated with a change in the risk of treatment failure (OR for each 10% increase in hospital use of oral steroids, ; 95% CI, -). A total of 1356 (22%) patients initially treated with oral steroids were switched to intravenous therapy later in the hospitalization.
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Help I have a friend who is a gym goer Im not sure of his quantity or how long he has been taking steroids, but stopped recently because he had really bad neck pain. No dr or scan, ultrasound etc showed anything. Put on huge pain killer amounts didnt help alot but felt after about six weeks some relief. Until today when he thinks a prior knee issue has flared up. If this a result of steroid abuse how long before it heals? Im pretty sure he wont touch them again. He can handle all over aches and pains but these last two injuries have had him off work.