Ecdysteroids bodybuilding

As for mechanisms of action, ecydsteroids seem to be able to cause a rapid Ca2+ influx in myocytes which leads to phosphorylation of Akt and thus protein synthesis. [1] This effect occurs after 10s of incubation, and is inhibited by PI3K inhibitors like seen in other studies, but also GPRC and PLC inhibitors; and when the cells are depleted of intra-cellular calcium Akt does not get phosphoraylized, and binding free calcium with EGTA lowered protein synthesis from 16% to 8%. [1] Calcium per se can be an important mediator of Akt and protein synthesis [51] , and ecdysteroids seem to work vicariously through Ca2+ and Akt. [52]

The second main ingredient in Super Rhanderol is diosgenin, more commonly known as wild yam extract.  Diosgenin is a type of steroidal saponin. These compounds serve as a starting point for the semisynthesis of certain steroid hormones.  Studies specific to saponins and their effects on ecdysteroids show that the saponins enhance membrane permeation of cells to allow for an increase in the effectiveness of the ecdysteroids.  Diosgenin has been included in Super Rhanderol in order to enhance the effects of the Rhaponticum.

Ecdysteroids bodybuilding

ecdysteroids bodybuilding

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