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Additionally, the following adverse reactions have been identified during the post approval use of the Astelin brand of azelastine hydrochloride % nasal spray (total daily dose mg to mg). Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Adverse reactions reported include the following: anaphylactoid reaction, application site irritation, facial edema, paroxysmal sneezing, tolerance, urinary retention, and xerophthalmia .
The most common side effects associated with fluticasone are headache , throat infection, nasal irritation, sneezing , cough , nausea , vomiting . Hypersensitivity reactions such as skin rash , itching , facial swelling, and anaphylaxis may occur. Some children may experience growth suppression when using fluticasone. A bloody nasal discharge ( nosebleed ) and septum perforation may occur. Fungal infection of the nose and throat, glaucoma , and cataracts are also associated with intranasal fluticasone.