Corticosteroid induced hypertension

Long term use of topical corticosteroids can induce tachyphylaxis (tolerance to the vasoconstrictive action of topical corticosteroids). Adverse effects are uncommon when using mild to potent corticosteroids for less than three months, except when used on the face and neck, in intertriginous areas (skin folds), or under occlusion. However, very potent corticosteroids should not be used continuously for longer than three weeks. 2 If longer use of very potent corticosteroids is required, they should be gradually tapered to avoid rebound symptoms and then stopped for a period of at least one week after which treatment can be resumed. 2

The association linking corticosteroid therapy with the development of posterior subcapsular cataracts has been well documented. These drugs are widely used therapeutically, principally to capitalize on their ability to inhibit inflammatory responses. The literature on corticosteroid-induced posterior subcapsular cataracts is reviewed here. Data from the previously published series and individual lens susceptibility to corticoids do not allow the establishment of a direct factor relating cataract formation to corticosteroid dose and the duration of therapy; however, significant progress has been made in elucidating the mechanism by which corticoids bring about the development of these opacities. Exploration into the development of these lesions has shed light on the similarities these opacities share with other cataracts, especially with regard to location and pathogenesis.

Triamcinolone is used to treat a number of different medical conditions, such as eczema , Lichen sclerosus , psoriasis , arthritis , allergies , ulcerative colitis , lupus , sympathetic ophthalmia , temporal arteritis , uveitis , ocular inflammation , Urushiol-induced contact dermatitis , aphthous ulcers (usually as triamcinolone acetonide ), visualization during vitrectomy and the prevention of asthma attacks. It will not treat an asthma attack once it has already begun. [2] [3] [4] It has also been used off-label for macular degeneration . [5]

Corticosteroid induced hypertension

corticosteroid induced hypertension

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